amphetamine and dextroamphetamine

am-FET-a-meen a-SPAR-tate, am-FET-a-meen SUL-fate, dex-troe-am-FET-a-meen SAK-a-rate, dex-troe-am-FET-a-meen SUL-fate

Oral route(Tablet;Capsule, Extended Release)

Amphetamines have a high potential for abuse, and administration for prolonged periods of time may lead to drug dependence and must be avoided. Misuse of amphetamines may cause sudden death and serious cardiovascular adverse events .

Commonly used brand name(s)

In the U.S.

• Adderall


• Adderall XR

Available Dosage Forms:

• Tablet


• Capsule, Extended Release

Therapeutic Class: CNS Stimulant

Chemical Class: Amphetamine

Uses For amphetamine and dextroamphetamine

Amphetamine and dextroamphetamine combination belongs to the group of medicines called central nervous system (CNS) stimulants. It is used to treat attention-deficit hyperactivity disorder (ADHD) and narcolepsy (uncontrollable desire for sleep or sudden attacks of deep sleep) .

Amphetamine and dextroamphetamine combination increases attention and decreases restlessness in patients who are overactive, cannot concentrate for very long or are easily distracted, and have unstable emotions. It is also used as part of a total treatment program that also includes social, educational, and psychological treatment .

Amphetamine and dextroamphetamine combination may also be used for other conditions as determined by your doctor .

amphetamine and dextroamphetamine is available only with a doctor's prescription. Prescriptions cannot be refilled. A new prescription must be obtained from your doctor each time you or your child needs amphetamine and dextroamphetamine .

Before Using amphetamine and dextroamphetamine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For amphetamine and dextroamphetamine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to amphetamine and dextroamphetamine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of amphetamine and dextroamphetamine combination in children with attention-deficit hyperactivity disorder below 3 years of age. Safety and efficacy have not been established .

Geriatric

Appropriate studies on the relationship of age to the effects of amphetamine and dextroamphetamine combination have not been performed in the geriatric population .

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using amphetamine and dextroamphetamine.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking amphetamine and dextroamphetamine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using amphetamine and dextroamphetamine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Clorgyline


• Furazolidone


• Iproniazid


• Isocarboxazid


• Moclobemide


• Nialamide


• Pargyline


• Phenelzine


• Procarbazine


• Rasagiline


• Selegiline


• Sibutramine


• Toloxatone


• Tranylcypromine

Using amphetamine and dextroamphetamine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Chlorpromazine


• Citalopram


• Furazolidone


• Venlafaxine

Using amphetamine and dextroamphetamine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Guanethidine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Other Medical Problems

The presence of other medical problems may affect the use of amphetamine and dextroamphetamine. Make sure you tell your doctor if you have any other medical problems, especially:

• Agitation, anxiety, or tension or


• Arteriosclerosis (hardening of the arteries), severe or


• Drug abuse or dependence, history of or


• Glaucoma or


• Heart disease or


• High blood pressure, moderate to severe or


• Overactive thyroid—amphetamine and dextroamphetamine should not be used in patients with these conditions .

• Heart problems or defects or


• High blood pressure, mild or


• Mental illness (e.g., aggressive behavior, hostility, psychosis, mania, family history of suicide, bipolar illness, depression) or


• Seizures, history of or


• Thyroid problems—Use with caution. Serious side effects may occur .

• Tourette's syndrome, history of or other tics—Children and their families should be checked by their doctor for this condition before taking amphetamine and dextroamphetamine .

Proper Use of amphetamine and dextroamphetamine

Take amphetamine and dextroamphetamine only as directed by your doctor. Do not take more or less of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much is taken, it may become habit-forming (causing mental or physical dependence) .

If you think amphetamine and dextroamphetamine is not working properly after you have taken it for several weeks, do not increase the dose. Instead, check with your doctor .

amphetamine and dextroamphetamine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions .

Swallow the extended-release capsule whole with water or other liquids. If you cannot swallow the extended-release capsule, you may open it and sprinkle the medicine into a small amount of applesauce. Stir this mixture well and swallow it right away without chewing. Do not store this mixture for future use. Do not crush or chew the medicine inside the capsule .

You may take the extended-release capsule with or without food .

Dosing

The dose of amphetamine and dextroamphetamine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of amphetamine and dextroamphetamine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (tablets):
  
  • For attention-deficit hyperactivity disorder:
    
    • Adults and children 6 years of age and older—At first, 5 milligrams (mg) one to two times a day. Your doctor may increase your dose if needed.
    
    
    • Children 3 to 5 years of age—At first, 2.5 mg daily. Your doctor may increase your dose if needed.
    
    
    • Children younger than 3 years of age—Use is not recommended .
    
    
  
  
  • For narcolepsy:
    
    • Adults, teenagers, and children 12 years of age and older—At first, 10 mg daily. Your doctor may adjust your dose if needed.
    
    
    • Children 6 to 12 years of age—At first, 5 mg daily. Your doctor may increase your dose if needed.
    
    
    • Children younger than 6 years of age—Dose must be determined by your doctor .
    
    
  
  

• For oral dosage form (extended-release capsules):
  
  • For attention-deficit hyperactivity disorder:
    
    • Adults—20 milligrams (mg) once a day in the morning.
    
    
    • Children and teenagers 6 to 17 years of age—At first, 10 milligrams (mg) once a day in the morning. Your doctor may adjust your dose if needed.
    
    
    • Children younger than 6 years of age—Dose must be determined by your doctor .
    
    
  
  

Missed Dose

If you miss a dose of amphetamine and dextroamphetamine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using amphetamine and dextroamphetamine

It is very important that your doctor check your progress at regular visits to make sure amphetamine and dextroamphetamine is working properly and to check for unwanted effects .

If you will be taking amphetamine and dextroamphetamine in large doses for a long time, do not stop taking it without first checking with your doctor. Your doctor may want you to reduce gradually the amount you are taking before stopping completely .

Do not take amphetamine and dextroamphetamine within 14 days of taking an MAO inhibitor such as Eldepryl®, Marplan®, Nardil®, or Parnate®.

amphetamine and dextroamphetamine may cause some people to feel a false sense of well-being or to become dizzy, lightheaded, or less alert than they are normally. Make sure you know how you react to amphetamine and dextroamphetamine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert.

Check with your doctor immediately if blurred vision, difficulty in reading, or any other change in vision occurs during or after treatment. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor) .

If you have been using amphetamine and dextroamphetamine for a long time and you think you may have become mentally or physically dependent on it, check with your doctor. Some signs of dependence on amphetamines are:

• A strong desire or need to continue taking the medicine.


• A need to increase the dose to receive the effects of the medicine.


• Withdrawal effects (for example, mental depression, nausea or vomiting, stomach cramps or pain, trembling, unusual tiredness or weakness) occurring after the medicine is stopped .

amphetamine and dextroamphetamine may cause slow growth. If your child is using amphetamine and dextroamphetamine, the doctor will need to keep track of your child's height and weight to make sure that your child is growing properly .

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements .

Before you have any medical tests, tell the medical doctor in charge that you are taking amphetamine and dextroamphetamine. The results of some tests may be affected by amphetamine and dextroamphetamine .

amphetamine and dextroamphetamine Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Bladder pain


• bloody or cloudy urine


• difficult, burning, or painful urination


• fast, pounding, or irregular heartbeat or pulse


• frequent urge to urinate


• lower back or side pain

Less common

• Cold flu-like symptoms


• cough or hoarseness


• fever or chills

Incidence not known

• Blistering, peeling, loosening of skin


• chest pain or discomfort


• confusion


• convulsions


• diarrhea


• difficulty breathing


• difficulty in speaking


• difficulty swallowing


• dizziness


• double vision


• faintness


• hallucinations (seeing, hearing, or feeling things that are not there)


• headache


• inability to move arms, legs, or facial muscles


• inability to speak


• itching


• joint or muscle pain


• large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs


• loss of bladder control


• muscle spasm or jerking of all extremities


• nausea


• pain or discomfort in arms, jaw, back, or neck


• red irritated eyes


• red skin lesions, often with a purple center


• severe mental changes


• shortness of breath


• skin rash


• slow speech


• sore throat


• sores, ulcers, or white spots in mouth or on lips


• sudden loss of consciousness


• sweating


• swelling of feet or lower legs


• tightness in chest


• troubled breathing


• uncontrolled vocal outbursts and/or tics (uncontrolled repeated body movements)


• unusual tiredness or weakness


• vomiting


• wheezing

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Blurred vision


• dark-colored urine


• discouragement


• dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly


• feeling sad or empty


• irritability


• lack of appetite


• loss of interest or pleasure


• muscle cramps or spasms


• muscle pain or stiffness


• nervousness


• overactive reflexes


• physical attempt to injure


• restlessness


• stomach cramps


• trembling or shaking of legs, arms, hands, or feet


• trouble concentrating


• trouble sleeping


• violent actions


• panic state


• pounding in the ears

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Anxiety


• dry mouth


• lack or loss of strength


• sleeplessness


• stomach pain


• unable to sleep


• weight loss

Incidence not known

• Constipation


• decreased interest in sexual intercourse


• false or unusual sense of well-being


• inability to have or keep an erection


• loss in sexual ability, desire, drive, or performance


• twitching, twisting, uncontrolled repetitive movements of tongue, lips, face, arms, or legs

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: amphetamine and dextroamphetamine side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

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More amphetamine and dextroamphetamine resources

• Amphetamine and dextroamphetamine Side Effects (in more detail)
• Amphetamine and dextroamphetamine Use in Pregnancy & Breastfeeding
• Drug Images
• Amphetamine and dextroamphetamine Drug Interactions
• Amphetamine and dextroamphetamine Support Group
• 212 Reviews for Amphetamine and dextroamphetamine - Add your own review/rating

Compare amphetamine and dextroamphetamine with other medications

• ADHD
• Fatigue
• Narcolepsy

Enalapril / Hydrochloorthiazide Hexal

Enalapril / Hydrochloorthiazide Hexal may be available in the countries listed below.

Ingredient matches for Enalapril / Hydrochloorthiazide Hexal

Enalapril

Enalapril maleate (a derivative of Enalapril) is reported as an ingredient of Enalapril / Hydrochloorthiazide Hexal in the following countries:

• Netherlands

Hydrochlorothiazide

Hydrochlorothiazide is reported as an ingredient of Enalapril / Hydrochloorthiazide Hexal in the following countries:

• Netherlands

International Drug Name Search

Magnesio Solfato Salf

Magnesio Solfato Salf may be available in the countries listed below.

Ingredient matches for Magnesio Solfato Salf

Magnesium Sulfate

Magnesium Sulfate is reported as an ingredient of Magnesio Solfato Salf in the following countries:

• Italy

International Drug Name Search

Crafilm

Crafilm may be available in the countries listed below.

Ingredient matches for Crafilm

Sucralfate

Sucralfate is reported as an ingredient of Crafilm in the following countries:

• Italy

International Drug Name Search

Depnon

Depnon may be available in the countries listed below.

Ingredient matches for Depnon

Mianserin

Mianserin hydrochloride (a derivative of Mianserin) is reported as an ingredient of Depnon in the following countries:

• India

International Drug Name Search

Amoxicillina Sandoz

Amoxicillina Sandoz may be available in the countries listed below.

Ingredient matches for Amoxicillina Sandoz

Amoxicillin

Amoxicillin trihydrate (a derivative of Amoxicillin) is reported as an ingredient of Amoxicillina Sandoz in the following countries:

• Italy

International Drug Name Search

Medamol

Medamol may be available in the countries listed below.

Ingredient matches for Medamol

Codeine

Codeine phosphate hemihydrate (a derivative of Codeine) is reported as an ingredient of Medamol in the following countries:

• Greece

Paracetamol

Paracetamol is reported as an ingredient of Medamol in the following countries:

• Greece


• Oman

International Drug Name Search

Disalcid

Generic Name: salsalate (SAL sa late)

Brand Names: Disalcid, Salsitab

What is Disalcid (salsalate)?

Salsalate is a non-steroidal anti-inflammatory drug (NSAID) in a group of drugs called salicylates (sa-LIS-il-ates). This medicine works by reducing substances in the body that cause pain, fever, and inflammation.

Salsalate is used to reduce pain, swelling, and joint stiffness caused by arthritis.

Salsalate may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Disalcid (salsalate)?

You should not use this medication if you are allergic to aspirin or to an NSAID (non-steroidal anti-inflammatory drug).

Before taking salsalate, tell your doctor if you have asthma, heart disease, high blood pressure, stomach or intestinal bleeding, diabetes, anemia, a bleeding disorder, liver or kidney disease, nasal polyps, a genetic enzyme deficiency, or if you are dehydrated.

This medicine may cause life-threatening heart or circulation problems such as heart attack or stroke, especially if you use it long term. Do not use salsalate just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Get emergency medical help if you have chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance.

This medicine may also cause serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking salsalate, especially in older adults.

Call your doctor at once if you have symptoms of stomach bleeding such as black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. This medication should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox. Salicylates can cause a serious and sometimes fatal condition called Reye's syndrome in children.

What should I discuss with my healthcare provider before taking Disalcid (salsalate)?

Salicylates may cause life-threatening heart or circulation problems such as heart attack or stroke, especially if you use it long term. Do not use salsalate just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Salicylates may also cause serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking salsalate, especially in older adults.

You should not use this medication if you are allergic to aspirin or to an NSAID (non-steroidal anti-inflammatory drug).

To make sure you can safely take salsalate, tell your doctor if you have any of these other conditions:

• 
  

  asthma;

  
  


• 
  

  heart disease, high blood pressure, congestive heart failure;

  
  


• 
  

  a history of stroke or heart attack;

  
  


• 
  

  a stomach ulcer or intestinal bleeding;

  
  


• 
  

  a bleeding or blood clotting disorder;

  
  


• 
  

  diabetes;

  
  


• 
  

  swelling or fluid retention;

  
  


• 
  

  anemia (a lack of red blood cells);

  
  


• liver disease;


• kidney disease;


• 
  

  an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);

  
  


• 
  

  nasal polyps; or

  
  


• 
  

  if you are dehydrated.

  
  

FDA pregnancy category C. Salsalate may be harmful to an unborn baby if the mother takes the medication during the last 3 months of pregnancy. Do not take this medication without telling your doctor if you are pregnant or plan to become pregnant during treatment. Salsalate can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. This medication should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox. Salicylates can cause a serious and sometimes fatal condition called Reye's syndrome in children. Older adults may be more likely to have side effects from salsalate.

How should I take Disalcid (salsalate)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Salsalate may be taken up to 3 times per day. Follow your doctor's instructions.

Take the medicine with a full glass of water. Take salsalate with food, milk, or an antacid if it upsets your stomach. To prevent stomach upset, do not lie down for at least 30 minutes after taking salsalate. It may take up to 2 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 2 weeks of treatment.

This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using salsalate.

If you need surgery, tell the surgeon ahead of time that you are using salsalate. You may need to stop using the medicine for a short time. Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Since salsalate is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include ringing in your ears, severe dizziness or drowsiness, sweating, fast breathing, severe vomiting or diarrhea, confusion, or seizure (convulsions).

What should I avoid while taking Disalcid (salsalate)?

Salsalate may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Ask a doctor or pharmacist before using any other over-the-counter medicine. Salicylates and NSAIDs are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains aspirin, ibuprofen, naproxen, ketoprofen, magnesium salicylate, or similar medicines.

If you are also taking low-dose aspirin because your doctor has prescribed it to prevent heart attack or stroke, do not stop taking it or change your dose without your doctor's advice. Aspirin should be used for cardiovascular conditions only under the supervision of a doctor.

Avoid drinking alcohol. It may increase your risk of stomach bleeding. Avoid smoking, since it can also increase your risk of stomach bleeding.

Disalcid (salsalate) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have a serious side effect such as:

• 
  

  chest pain, severe dizziness, shortness of breath, slurred speech, problems with vision or balance;

  
  


• 
  

  sudden numbness or weakness, especially on one side of the body;

  
  


• 
  

  feeling like you might pass out;

  
  


• 
  

  black, bloody, or tarry stools;

  
  


• 
  

  coughing up blood or vomit that looks like coffee grounds;

  
  


• 
  

  hearing problems, ringing in your ears;

  
  


• 
  

  swelling in your hands or feet, rapid weight gain;

  
  


• 
  

  fast or pounding heartbeats;

  
  


• 
  

  easy bruising or bleeding, fever, chills, sore throat, flu symptoms;

  
  


• 
  

  urinating more or less than usual;

  
  


• 
  

  severe stomach pain, ongoing nausea or vomiting; or

  
  


• 
  

  dark urine, jaundice (yellowing of the skin or eyes).

  
  

Less serious side effects may include:

• 
  

  upset stomach, heartburn; or

  
  


• 
  

  mild dizziness.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Disalcid (salsalate)?

Many drugs can interact with salsalate. Below is just a partial list. Tell your doctor if you are using:

• 
  

  acetazolamide (Diamox);

  
  


• 
  

  cyclosporine (Gengraf, Neoral, Sandimmune);

  
  


• 
  

  lithium (Eskalith, LithoBid);

  
  


• 
  

  methotrexate (Rheumatrex, Trexall);

  
  


• 
  

  pemetrexed (Alimta);

  
  


• 
  

  tenofovir (Viread);

  
  


• 
  

  an antidepressant such as fluoxetine (Prozac) or sertraline (Zoloft);

  
  


• 
  

  a blood thinner such as warfarin (Coumadin);

  
  


• 
  

  oral diabetes medication;

  
  


• 
  

  a diuretic (water pill);

  
  


• 
  

  gout medication such as probenecid (Benemid);

  
  


• 
  

  heart or blood pressure medication such as atenolol (Tenormin), captopril (Capoten), lisinopril (Prinivil, Zestril), losartan (Cozaar, Hyzaar), metoprolol (Lopressor, Toprol), and others;

  
  


• 
  

  medication used to prevent blood clots, such as cilostazol (Pletal) or clopidogrel (Plavix);

  
  


• 
  

  osteoporosis medication such as alendronate (Fosamax), ibandronate (Boniva), risedronate (Actonel), and others;

  
  


• 
  

  sodium bicarbonate, potassium citrate (K-Lyte, Urocit-K), sodium citrate and citric acid (Bicitra, Oracit), or sodium citrate and potassium (Citrolith, Polycitra);

  
  


• 
  

  seizure medication such as phenytoin (Dilantin), phenobarbital (Solfoton), valproic acid (Depakene); or

  
  


• 
  

  steroid medicine (prednisone and others).

  
  

This list is not complete and there are many other drugs that can interact with salsalate. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

More Disalcid resources

• Disalcid Side Effects (in more detail)
• Disalcid Use in Pregnancy & Breastfeeding
• Drug Images
• Disalcid Drug Interactions
• Disalcid Support Group
• 1 Review for Disalcid - Add your own review/rating

• Salsalate Prescribing Information (FDA)


• Salsalate Monograph (AHFS DI)


• Amigesic Advanced Consumer (Micromedex) - Includes Dosage Information


• Amigesic MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Disalcid with other medications

• Osteoarthritis
• Rheumatoid Arthritis

Where can I get more information?

• Your pharmacist can provide more information about salsalate.

See also: Disalcid side effects (in more detail)

Dapiprazole

Generic Name: Dapiprazole (da-PI-pray-zole)
Brand Name: Rev-Eyes

Dapiprazole is used for:

Decreasing the size of the pupil after certain eye examinations or surgery.

Dapiprazole is an antimydriatic. It works by blocking the smooth muscle contraction of the iris, which helps to decrease the size of the pupil.

Do NOT use Dapiprazole if:

• you are allergic to any ingredient in Dapiprazole


• you have acute iritis (inflammation of the front portion of the eye)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Dapiprazole:

Some medical conditions may interact with Dapiprazole. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Dapiprazole. However, no specific interactions with Dapiprazole are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Dapiprazole may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Dapiprazole:

Use Dapiprazole as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Dapiprazole is usually administered at your doctor's office, hospital, or clinic.


• Dapiprazole is for use in the eye only. Avoid contact with other mucous membranes.


• Dapiprazole must be mixed before using. To use Dapiprazole, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them. To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including your eye. Keep the container tightly closed.


• If Dapiprazole is cloudy or discolored, do not use it.


• If you miss a dose of Dapiprazole, contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Dapiprazole.

Important safety information:

• Dapiprazole may cause blurred vision or difficulty seeing in the dark. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Dapiprazole. Using Dapiprazole alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.


• Patients should not receive Dapiprazole more often than once per week.


• Use Dapiprazole with extreme caution in CHILDREN younger than 4 years of age. Safety and effectiveness in this age group have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Dapiprazole, discuss with your doctor the benefits and risks of using Dapiprazole during pregnancy. It is unknown if Dapiprazole is excreted in breast milk. If you are or will be breast-feeding while you are using Dapiprazole, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Dapiprazole:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Headache; light sensitivity; redness and itching of the eyelids; redness or burning when you first put the medicine in your eye.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); swelling of the eyelid.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Dapiprazole side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Dapiprazole:

Store mixed medicine at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), for 21 days. If Dapiprazole is cloudy or discolored, discard it. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Dapiprazole out of the reach of children and away from pets.

General information:

• If you have any questions about Dapiprazole, please talk with your doctor, pharmacist, or other health care provider.


• Dapiprazole is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Dapiprazole. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Dapiprazole resources

• Dapiprazole Side Effects (in more detail)
• Dapiprazole Use in Pregnancy & Breastfeeding
• Dapiprazole Support Group
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