Saturday, March 31, 2012

neostigmine


nee-oh-STIG-meen


Commonly used brand name(s)

In the U.S.


  • Prostigmin Bromide

Available Dosage Forms:


  • Tablet

Therapeutic Class: Central Nervous System Agent


Pharmacologic Class: Cholinesterase Inhibitor


Uses For neostigmine


Neostigmine is used to treat a muscle disease called myasthenia gravis. .


neostigmine is available only with your doctor's prescription .


Before Using neostigmine


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For neostigmine , the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to neostigmine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies have not been performed on the relationship of age to the effects of neostigmine in the pediatric population. Safety and efficacy have not been established .


Geriatric


No information is available on the relationship of age to the effects of neostigmine in geriatric patients .


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking neostigmine , it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using neostigmine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Succinylcholine

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of neostigmine . Make sure you tell your doctor if you have any other medical problems, especially:


  • Intestine blockage (blocked gut or abdomen) or

  • Kidney blockage (blocked urine flow) or

  • Peritonitis (lining of the abdomen is inflamed)—Should not be used in patients with these conditions.

  • Asthma or

  • Bradycardia (slow heartbeat) or

  • Heart attack, recent or

  • Heart rhythm problems or

  • Overactive thyroid or

  • Seizures or

  • Stomach ulcer—Use with caution. May make these conditions worse.

Proper Use of neostigmine


It is important to keep a daily record of when you take each dose and how long it lasts. This will help your doctor decide if your dose needs to be adjusted .


Dosing


The dose of neostigmine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of neostigmine . If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For oral dosage form (tablets):
    • For myasthenia gravis:
      • Adults—The usual dose is 15 to 375 milligrams (mg) each day, given in divided doses. Your doctor may adjust your dose if needed.

      • Children—Use and dose must be determined by your doctor .



Missed Dose


If you miss a dose of neostigmine , take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions While Using neostigmine


It is very important that your doctor check your progress at regular visits to make sure that neostigmine is working properly and to check for unwanted effects .


If your symptoms do not improve or if they become worse, check with your doctor .


neostigmine Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


More common
  • Twitches of the muscle visible under the skin

Incidence not known
  • Blurred or loss of vision

  • changes in patterns and rhythms of speech

  • chest pain or discomfort

  • confusion

  • cough

  • difficult or labored breathing

  • difficulty in moving

  • difficulty swallowing

  • disturbed color perception

  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly

  • double vision

  • fast, pounding, or irregular heartbeat or pulse

  • halos around lights

  • hives

  • irregular, fast or slow, or shallow breathing

  • itching

  • lightheadedness, dizziness, or fainting

  • loss of consciousness

  • muscle cramps and spasms

  • muscle pain or stiffness

  • night blindness

  • no blood pressure or pulse

  • noisy breathing

  • overbright appearance of lights

  • pain in joints

  • pale or blue lips, fingernails, or skin

  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

  • seizures

  • shortness of breath

  • skin rash

  • slow or irregular heartbeat

  • slurred speech

  • stopping of heart

  • sweating

  • tightness in chest

  • trouble in speaking

  • tunnel vision

  • unconsciousness

  • unusual tiredness or weakness

  • wheezing

Get emergency help immediately if any of the following symptoms of overdose occur:


Symptoms of Overdose
  • Constipation

  • decreased sexual ability

  • difficult urination

  • dry mouth

  • enlarged pupils

  • muscle weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Increased watering of mouth

Incidence not known
  • Bloated

  • constricted, pinpoint, or small pupils (black part of eye)

  • diarrhea

  • drowsiness

  • excess air or gas in stomach or intestines

  • feeling of warmth

  • full feeling

  • headache

  • increase in mucous from lungs

  • increased need to urinate

  • increased sweating

  • nausea

  • passing gas

  • passing urine more often

  • redness of skin

  • redness of the face, neck, arms and occasionally, upper chest

  • skin rash

  • stomach cramps

  • vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: neostigmine side effects (in more detail)



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More neostigmine resources


  • Neostigmine Side Effects (in more detail)
  • Neostigmine Use in Pregnancy & Breastfeeding
  • Neostigmine Drug Interactions
  • Neostigmine Support Group
  • 0 Reviews for Neostigmine - Add your own review/rating


  • neostigmine Concise Consumer Information (Cerner Multum)

  • Neostigmine MedFacts Consumer Leaflet (Wolters Kluwer)

  • Neostigmine Professional Patient Advice (Wolters Kluwer)

  • Neostigmine Bromide Monograph (AHFS DI)



Compare neostigmine with other medications


  • Myasthenia Gravis

Friday, March 30, 2012

Ionsys device


Generic Name: fentanyl transdermal (device) (FEN ta nil trans DERM al)

Brand Names: Ionsys


What is fentanyl transdermal?

Fentanyl is a narcotic (opioid) pain medicine.


The fentanyl transdermal device is used only in a hospital to treat acute pain after surgery.


Fentanyl transdermal may be used for other purposes not listed in this medication guide.


What is the most important information I should know about a fentanyl transdermal device?


The fentanyl transdermal device is used only while you are in a hospital. You will not be allowed to use the device at home. Do not leave the hospital with a device on your skin. Do not use this medication unless you are already being treated with a similar opioid (narcotic) pain medicine and your body is tolerant to it. Talk with your doctor if you are not sure you are opioid-tolerant. Fentanyl may be habit-forming and should be used only by the person it was prescribed for. This medication should never be shared with another person, especially someone who has a history of drug abuse or addiction.

Avoid drinking alcohol, or using other medicines that make you sleepy (such as cold medicine, other pain medication, muscle relaxers, and medicine for depression or anxiety). They can add to extreme drowsiness or breathing problems caused by fentanyl.


The fentanyl transdermal device may burn your skin if you wear the patch during an MRI (magnetic resonance imaging). Remove the device before undergoing such a test.

What should I discuss with my healthcare provider before using a fentanyl transdermal device?


Do not use this medication unless you are already being treated with a similar opioid (narcotic) pain medicine and your body is tolerant to it. Opioid medicines include morphine (Kadian, MS Contin, Oramorph, and others), oxycodone (OxyContin), and hydromorphone (Dilaudid). Talk with your doctor if you are not sure you are opioid-tolerant. Before you receive this medication, tell your doctor if you are allergic to fentanyl or any other medications, or if you have:

  • a breathing disorder such as chronic obstructive pulmonary disease (COPD);




  • a history of head injury or brain tumor;




  • a heart rhythm disorder;




  • liver disease; or




  • kidney disease.



If you have any of these conditions, you may need a dose adjustment or special tests to safely use this medication.


FDA pregnancy category C. This medication may be harmful to an unborn baby, and could cause addiction or withdrawal symptoms in a newborn. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Fentanyl may also cause addiction and withdrawal symptoms in a nursing infant. Do not use fentanyl transdermal without telling your doctor if you are breast-feeding a baby. Older adults may be more likely to have side effects from this medicine. Fentanyl transdermal may be habit-forming and should be used only by the person it was prescribed for. This medication should never be shared with another person, especially someone who has a history of drug abuse or addiction.

How is a fentanyl transdermal device used?


The fentanyl transdermal device is used only while you are in a hospital. You will not be allowed to use the device at home. Do not leave the hospital with a device on your skin.

If the skin must be washed before fentanyl transdermal is applied, use clear water only. Allow the skin to dry completely before applying the medicine.


Do not use soaps, oils, lotions, alcohol, or other chemicals on the skin where you will apply fentanyl transdermal. These substances could increase the amount of fentanyl that your skin absorbs, possibly causing harmful effects.

The device will be applied where you can reach it, such as your chest or the outer side of your upper arm. The device is worn for 24 hours or until the device has delivered 80 doses of fentanyl.


To release the medicine from the device, press the dosing button twice. The device will sound a beep when the dose starts, and a red light will come on for 10 minutes while the dose is delivered. The light will also flash between doses to let your caregivers know how many doses are left in the device. Tell your care provider if the patch comes loose or falls off.


The device will allow you to give yourself up to 6 doses per hour. Do not allow others to press the dosing button for you. The fentanyl transdermal device may burn your skin if you wear the patch during an MRI (magnetic resonance imaging). Remove the device before undergoing such a test.

What happens if I miss a dose?


Since a fentanyl transdermal device is applied by a healthcare professional in a hospital setting, it is not likely that you will miss a dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A fentanyl overdose can be fatal.

Overdose symptoms may include slow breathing, extreme weakness or dizziness, pinpoint pupils, cold and clammy skin, or fainting.


What should I avoid while using a fentanyl transdermal device?


This medication is for use only on the skin. Avoid touching the gel inside a device with your fingers. Do not allow the medicine to come into contact with your eyes, nose, mouth, or lips. If it does, rinse with water. Do not use soap or other chemicals. Fentanyl can cause side effects that may impair your thinking or reactions. Be careful if you do anything that requires you to be awake and alert. Avoid drinking alcohol, which can increase dizziness or drowsiness.

Fentanyl transdermal side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Tell your caregivers right away if you have any of these serious side effects:

  • weak, shallow breathing;




  • severe weakness, feeling light-headed or fainting;




  • cold, clammy skin; or




  • pale skin, easy bruising or bleeding.



Less serious side effects may include:



  • nausea, vomiting, stomach pain, constipation, gas;




  • dizziness, drowsiness, anxiety, sleep problems (insomnia);




  • muscle stiffness, back pain;




  • itching, blistering, redness, or swelling where the patch or device was worn; or




  • increased sweating, urinating less than usual.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect fentanyl transdermal?


Tell your doctor if you regularly use other medicines that make you sleepy (such as cold medicine, other pain medicine, muscle relaxers, and medicine for depression or anxiety). They can add to extreme drowsiness or breathing problems caused by fentanyl.

Tell your doctor about all other medicines you use, especially:



  • carbamazepine (Tegretol, Carbatrol);




  • phenytoin (Dilantin);




  • diltiazem (Cartia, Cardizem);




  • St. John's wort;




  • rifampin (Rifater, Rifamate, Rimactane);




  • an antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), or telithromycin (Ketek);




  • antifungal medication such as itraconazole (Sporanox), ketoconazole (Extina, Ketozole, Nizoral, Xolegal), miconazole (Oravig), or voriconazole (Vfend); or




  • HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), saquinavir (Invirase), or ritonavir (Norvir, Kaletra).



This list is not complete and other drugs may interact with fentanyl. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Ionsys resources


  • Ionsys Side Effects (in more detail)
  • Ionsys Use in Pregnancy & Breastfeeding
  • Ionsys Drug Interactions
  • Ionsys Support Group
  • 0 Reviews for Ionsys - Add your own review/rating


Compare Ionsys with other medications


  • Pain
  • Postoperative Pain


Where can I get more information?


  • Your pharmacist can provide more information about fentanyl transdermal.

See also: Ionsys side effects (in more detail)


Monday, March 26, 2012

Grifulvin V Microsize


Pronunciation: GRIS-ee-oh-FUL-vin
Generic Name: Griseofulvin
Brand Name: Generic only. No brands available.


Grifulvin V Microsize is used for:

Treating certain fungal infections (eg, ringworm) of the hair, skin, and nails. It may also be used for other conditions as determined by your doctor.


Grifulvin V Microsize is an antifungal agent. It works by making the skin more resistant to fungal growth.


Do NOT use Grifulvin V Microsize if:


  • you are allergic to any ingredient in Grifulvin V Microsize

  • you have liver failure or the blood disease porphyria

  • you are pregnant

Contact your doctor or health care provider right away if any of these apply to you.



Before using Grifulvin V Microsize:


Some medical conditions may interact with Grifulvin V Microsize. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to a penicillin antibiotic (eg, amoxicillin)

  • if you have liver disease or lupus

Some MEDICINES MAY INTERACT with Grifulvin V Microsize. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Barbiturates (eg, phenobarbital) because they may decrease Grifulvin V Microsize's effectiveness

  • Anticoagulants (eg, warfarin), cabazitaxel, cyclosporine, oral contraceptives (birth control pills), or ulipristal because their effectiveness may be decreased by Grifulvin V Microsize

This may not be a complete list of all interactions that may occur. Ask your health care provider if Grifulvin V Microsize may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Grifulvin V Microsize:


Use Grifulvin V Microsize as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Grifulvin V Microsize by mouth with or without food.

  • Shake well before each use.

  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.

  • To clear up your infection completely, use Grifulvin V Microsize for the full course of treatment. Keep using it even if you feel better in a few days.

  • If you miss a dose of Grifulvin V Microsize, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Grifulvin V Microsize.



Important safety information:


  • Grifulvin V Microsize may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Grifulvin V Microsize with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Be sure to take Grifulvin V Microsize for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The fungus could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

  • Do not drink alcohol while you are taking Grifulvin V Microsize.

  • Grifulvin V Microsize may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Grifulvin V Microsize. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.

  • It is important to practice good hygiene during and after use to prevent reinfection.

  • Hormonal birth control (eg, birth control pills) may not work as well while you are using Grifulvin V Microsize. To prevent pregnancy, use an extra form of birth control (eg, condoms).

  • Lab tests, including complete blood cell counts, liver function, and kidney function, may be performed while you use Grifulvin V Microsize. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Grifulvin V Microsize should be used with extreme caution in CHILDREN younger than 3 years old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: Do not take Grifulvin V Microsize if you are pregnant. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. If you are or will be breast-feeding while you use Grifulvin V Microsize, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Grifulvin V Microsize:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Diarrhea; dizziness; headache; nausea; stomach upset; tiredness; vomiting.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); butterfly-shaped rash on the face; confusion; fever, chills, or sore throat; flu-like symptoms (eg, headache, joint pain); mental or mood changes; numbness, burning, or tingling of the hands or feet; red, swollen, blistered or peeling skin; symptoms of liver problems (dark urine, pale stools, severe or persistent stomach pain, yellowing of the skin or eyes); white patches in the mouth.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Grifulvin V Microsize side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.


Proper storage of Grifulvin V Microsize:

Store Grifulvin V Microsize at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Keep Grifulvin V Microsize out of the reach of children and away from pets.


General information:


  • If you have any questions about Grifulvin V Microsize, please talk with your doctor, pharmacist, or other health care provider.

  • Grifulvin V Microsize is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Grifulvin V Microsize. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Grifulvin V Microsize resources


  • Grifulvin V Microsize Side Effects (in more detail)
  • Grifulvin V Microsize Use in Pregnancy & Breastfeeding
  • Drug Images
  • Grifulvin V Microsize Drug Interactions
  • Grifulvin V Microsize Support Group
  • 0 Reviews for Grifulvin V Microsize - Add your own review/rating


Compare Grifulvin V Microsize with other medications


  • Dermatophytosis
  • Onychomycosis, Fingernail
  • Onychomycosis, Toenail
  • Tinea Barbae
  • Tinea Capitis
  • Tinea Corporis
  • Tinea Cruris
  • Tinea Pedis

Friday, March 23, 2012

Theraflu Flu & Sore Throat (pseudoephedrine)


Generic Name: acetaminophen, chlorpheniramine, and pseudoephedrine (a seet a MIN oh fen, klor fen IR a meen, soo doe e FED rin)

Brand Names: Alka-Seltzer Plus Cold Liquigel, Allerest Headache Strength, Allerest Sinus, Cold Medicine Plus, Comtrex Allergy Sinus, Comtrex Allergy Sinus Maximum Strength, Comtrex Allergy Sinus Night and Day, Kolephrin, Sinarest, Sinutab Ex-Strength, Theraflu Cold & Sore Throat (pseudoephedrine), Theraflu Flu & Sore Throat (pseudoephedrine), Theraflu Maximum Strength


What is Theraflu Flu & Sore Throat (pseudoephedrine) (acetaminophen, chlorpheniramine, and pseudoephedrine)?

Acetaminophen is a pain reliever and fever reducer.


Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.


Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).


The combination of acetaminophen, chlorpheniramine, and pseudoephedrine is used to treat headache, fever, body aches, runny or stuffy nose, sneezing, itching, watery eyes, and sinus congestion caused by allergies, the common cold, or the flu.


Acetaminophen, chlorpheniramine, and pseudoephedrine may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Theraflu Flu & Sore Throat (pseudoephedrine) (acetaminophen, chlorpheniramine, and pseudoephedrine)?


Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Do not take this medication without a doctor's advice if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You should not use this medicine if you have severe constipation, a blockage in your stomach or intestines, or if you are unable to urinate. Do not use this medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, high blood pressure, heart disease, coronary artery disease, or overactive thyroid. Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen and can increase certain side effects of chlorpheniramine. Do not use this medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects. Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose.

What should I discuss with my healthcare provider before taking Theraflu Flu & Sore Throat (pseudoephedrine) (acetaminophen, chlorpheniramine, and pseudoephedrine)?


You should not use this medicine if you have severe constipation, a blockage in your stomach or intestines, or if you are unable to urinate. Do not take this medication without a doctor's advice if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You may not be able to take medicine that contains acetaminophen. Do not use this medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, high blood pressure, heart disease, coronary artery disease, or overactive thyroid. Do not use this medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:



  • liver disease, cirrhosis, or a history of alcoholism;




  • a blockage in your digestive tract (stomach or intestines);




  • diabetes;




  • kidney disease;




  • epilepsy or other seizure disorder;




  • cough with mucus, or cough caused by smoking, emphysema, or chronic bronchitis;




  • enlarged prostate or urination problems;




  • low blood pressure;




  • pheochromocytoma (an adrenal gland tumor); or




  • if you take potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K).




It is not known whether acetaminophen, chlorpheniramine, and pseudoephedrine will harm an unborn baby. Do not use this medicine without your doctor's advice if you are pregnant. This medication may pass into breast milk and may harm a nursing baby. Antihistamines and decongestants may also slow breast milk production. Do not use this medicine without your doctor's advice if you are breast-feeding a baby.

How should I take Theraflu Flu & Sore Throat (pseudoephedrine) (acetaminophen, chlorpheniramine, and pseudoephedrine)?


Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. This medicine is usually taken only for a short time until your symptoms clear up.


Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death.

Dissolve one packet of the powder in at least 4 ounces of water. Stir this mixture and drink all of it right away.


Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Do not take for longer than 7 days in a row. Stop taking the medicine and call your doctor if you still have a fever after 3 days of use, you still have pain after 7 days (or 5 days if treating a child), if your symptoms get worse, or if you have a skin rash, ongoing headache, or any redness or swelling.


If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken this medicine within the past few days. Store at room temperature away from moisture and heat. Do not allow liquid medicine to freeze.

What happens if I miss a dose?


Since this medicine is taken when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1 800 222 1222. An overdose of acetaminophen can be fatal.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.


Overdose symptoms may also include severe forms of some of the side effects listed in this medication guide.


What should I avoid while taking Theraflu Flu & Sore Throat (pseudoephedrine) (acetaminophen, chlorpheniramine, and pseudoephedrine)?


Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP. Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen, and can increase certain side effects of chlorpheniramine. This medicine may cause blurred vision or impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Theraflu Flu & Sore Throat (pseudoephedrine) (acetaminophen, chlorpheniramine, and pseudoephedrine) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have a serious side effect such as:

  • chest pain, rapid pulse, fast or uneven heart rate;




  • confusion, hallucinations, severe nervousness;




  • tremor, seizure (convulsions);




  • easy bruising or bleeding, unusual weakness;




  • urinating less than usual or not at all;




  • nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of your skin or eyes); or




  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, chest pain, shortness of breath, uneven heartbeats, seizure).



Less serious side effects may include:



  • dizziness, drowsiness;




  • mild headache;




  • dry mouth, nose, or throat;




  • constipation;




  • blurred vision;




  • feeling nervous; or




  • sleep problems (insomnia);



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Theraflu Flu & Sore Throat (pseudoephedrine) (acetaminophen, chlorpheniramine, and pseudoephedrine)?


Ask a doctor or pharmacist before using this medicine if you regularly use other medicines that make you sleepy (such as narcotic pain medication, sedatives, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by chlorpheniramine.

Tell your doctor about all other medicines you use, especially:



  • leflunomide (Arava);




  • topiramate (Topamax);




  • zonisamide (Zonegran);




  • an antibiotic, antifungal medicine, sulfa drug, or tuberculosis medicine;




  • an antidepressant;




  • birth control pills or hormone replacement therapy;




  • bladder or urinary medications;




  • blood pressure medication;




  • a bronchodilator;




  • cancer medicine;




  • cholesterol-lowering medications such as Lipitor, Niaspan, Zocor, Vytorin, and others;




  • gout or arthritis medications (including gold injections);




  • HIV/AIDS medication;




  • medication for nausea and vomiting, stomach ulcers, or irritable bowel syndrome;




  • medicines to treat psychiatric disorders;




  • an NSAID such as Advil, Aleve, Arthrotec, Cataflam, Celebrex, Indocin, Motrin, Naprosyn, Treximet, Voltaren, others; or




  • seizure medication.



This list is not complete and other drugs may interact with acetaminophen, chlorpheniramine, and pseudoephedrine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Theraflu Flu & Sore Throat (pseudoephedrine) resources


  • Theraflu Flu & Sore Throat (pseudoephedrine) Side Effects (in more detail)
  • Theraflu Flu & Sore Throat (pseudoephedrine) Use in Pregnancy & Breastfeeding
  • Theraflu Flu & Sore Throat (pseudoephedrine) Drug Interactions
  • Theraflu Flu & Sore Throat (pseudoephedrine) Support Group
  • 0 Reviews for Theraflu Flu & Sore Throat (pseudoephedrine) - Add your own review/rating


  • Children's Tylenol Cold Chewable Tablets MedFacts Consumer Leaflet (Wolters Kluwer)



Compare Theraflu Flu & Sore Throat (pseudoephedrine) with other medications


  • Cold Symptoms
  • Hay Fever


Where can I get more information?


  • Your pharmacist can provide more information about acetaminophen, chlorpheniramine, and pseudoephedrine.

See also: Theraflu Flu & Sore Throat (pseudoephedrine) side effects (in more detail)


Monday, March 12, 2012

Grape Seed


Pronunciation: Not applicable.
Generic Name: Grape Seed
Brand Name: Generics only. No brands available.


Grape Seed is used for:

Protecting against cancer and aging, improving circulation and wound healing, and reducing inflammation and collagen breakdown. It is also used for diabetes and retinopathy. Grape seed is promoted for use in atherosclerosis and peripheral vascular disease, claiming to improve pain relief, limb heaviness, and swelling in circulatory conditions, and to reduce heart attack and stroke. It may have other uses as well. Check with your pharmacist for more details regarding the particular brand you use.


Grape Seed is an herbal product. It works by increasing antioxidant activity in the body.


Do NOT use Grape Seed if:


  • you are allergic to any ingredient in Grape Seed, including grape seed

Contact your doctor or health care provider right away if any of these apply to you.



Before using Grape Seed:


Some medical conditions may interact with Grape Seed. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Grape Seed. However, no specific interactions are known at this time.


This may not be a complete list of all interactions that may occur. Ask your health care provider if Grape Seed may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Grape Seed:


Use Grape Seed as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Dosing depends on the use and the source of the product.

  • Use as directed on the package, unless instructed otherwise by your doctor.

  • If you miss taking a dose of Grape Seed for 1 or more days, there is no cause for concern. If your doctor recommended that you take it, try to remember your dose every day.

Ask your health care provider any questions you may have about how to use Grape Seed.



Important safety information:


  • If you have a circulation problem and your symptoms become worse, seek medical attention as soon as possible.

  • This product has not been approved by the Food and Drug Administration (FDA) as safe and effective for any medical condition. The long-term safety of herbal products is not known. Before using any alternative medicine, talk with your doctor or pharmacist.

  • PREGNANCY and BREAST-FEEDING: Do not use this product if you are pregnant. Do not breast-feed while taking this product.


Possible side effects of Grape Seed:


All medicines may cause side effects, but many people have no, or minor, side effects. No COMMON side effects have been reported with the proper use of Grape Seed. Seek medical attention right away if any of these SEVERE side effects occur:



Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in color, sensation, or temperature of a leg or arm.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Grape Seed side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.


Proper storage of Grape Seed:

Store at room temperature away from heat, moisture, and light unless otherwise directed on the package label. Do not store in the bathroom. Most herbal products are not in childproof containers. Keep Grape Seed out of the reach of children and away from pets.


General information:


  • If you have any questions about Grape Seed, please talk with your doctor, pharmacist, or other health care provider.

  • Grape Seed is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Grape Seed. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Grape Seed resources


  • Grape Seed Side Effects (in more detail)
  • Grape Seed Use in Pregnancy & Breastfeeding
  • Grape Seed Support Group
  • 0 Reviews for Grape Seed - Add your own review/rating


Compare Grape Seed with other medications


  • Herbal Supplementation

Sunday, March 11, 2012

QC Cough/Cold


Pronunciation: klor-fen-IHR-ah-meen/DEX-troe-meth-OR-fan
Generic Name: Chlorpheniramine/Dextromethorphan
Brand Name: Examples include Coricidin HBP Cough/Cold and QC Cough/Cold


QC Cough/Cold is used for:

Relieving cough and other symptoms such as runny nose and sneezing due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.


QC Cough/Cold is an antihistamine and cough suppressant combination. It works by blocking the action of histamine, which reduces allergy symptoms such as watery eyes and sneezing. The cough suppressant works in the brain to help decrease the cough reflex.


Do NOT use QC Cough/Cold if:


  • you are allergic to any ingredient in QC Cough/Cold

  • you take sodium oxybate (GHB) or if you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.



Before using QC Cough/Cold:


Some medical conditions may interact with QC Cough/Cold. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, plan to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a fast, slow, or irregular heartbeat

  • if you have a history of asthma, lung problems (eg, emphysema), adrenal gland problems (eg, adrenal gland tumor), heart problems, high blood pressure, diabetes, heart blood vessel problems, stroke, glaucoma, a blockage of your stomach or intestines, ulcers, a blockage of your bladder, trouble urinating, enlarged prostate, seizures, or an overactive thyroid

Some MEDICINES MAY INTERACT with QC Cough/Cold. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Furazolidone, MAO inhibitors (eg, phenelzine), or sodium oxybate (GHB) because the risk of serious side effects, such as severe low blood pressure, severe drowsiness, breathing problems, fever, severe muscle problems, and possibly death, may be increased by QC Cough/Cold

  • Anticoagulants (eg, warfarin) because the risk of side effects, such as bleeding, may be increased by QC Cough/Cold

  • Isoniazid because side effects of QC Cough/Cold may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if QC Cough/Cold may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use QC Cough/Cold:


Use QC Cough/Cold as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • QC Cough/Cold may be taken with or without food.

  • If you miss a dose of QC Cough/Cold, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use QC Cough/Cold.



Important safety information:


  • QC Cough/Cold may cause dizziness, drowsiness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to QC Cough/Cold. Using QC Cough/Cold alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.

  • Do NOT exceed the recommended dose or take QC Cough/Cold for longer than prescribed without checking with your doctor.

  • If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.

  • QC Cough/Cold may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to QC Cough/Cold. Use a sunscreen or protective clothing if you must be outside for a prolonged period.

  • If you are scheduled for allergy skin testing, do not take QC Cough/Cold for several days before the test because it may decrease your response to the skin tests.

  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using QC Cough/Cold.

  • Use QC Cough/Cold with caution in the ELDERLY because they may be more sensitive to its effects.

  • Caution is advised when using QC Cough/Cold in CHILDREN because they may be more sensitive to its effects.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking QC Cough/Cold, discuss with your doctor the benefits and risks of using QC Cough/Cold during pregnancy. It is unknown if QC Cough/Cold is excreted in breast milk. Do not breast-feed while taking QC Cough/Cold.


Possible side effects of QC Cough/Cold:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; trouble sleeping; vision changes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: QC Cough/Cold side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.


Proper storage of QC Cough/Cold:

Store QC Cough/Cold at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep QC Cough/Cold out of the reach of children and away from pets.


General information:


  • If you have any questions about QC Cough/Cold, please talk with your doctor, pharmacist, or other health care provider.

  • QC Cough/Cold is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about QC Cough/Cold. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More QC Cough/Cold resources


  • QC Cough/Cold Side Effects (in more detail)
  • QC Cough/Cold Use in Pregnancy & Breastfeeding
  • QC Cough/Cold Drug Interactions
  • QC Cough/Cold Support Group
  • 0 Reviews for QC Cough/Cold - Add your own review/rating


Compare QC Cough/Cold with other medications


  • Cough and Nasal Congestion

Thursday, March 8, 2012

Apriso


Generic Name: mesalamine (Oral route)

me-SAL-a-meen

Commonly used brand name(s)

In the U.S.


  • Apriso

  • Asacol

  • Asacol HD

  • Lialda

  • Pentasa

In Canada


  • Asacol 800

Available Dosage Forms:


  • Tablet, Delayed Release

  • Tablet, Enteric Coated

  • Capsule, Extended Release

  • Tablet

Therapeutic Class: Anti-Inflammatory


Chemical Class: Salicylate, Non-Aspirin


Uses For Apriso


Mesalamine is used to treat and prevent an inflammatory bowel disease called ulcerative colitis. It works inside the intestines (bowel) to reduce the inflammation and other symptoms of the disease.


This medicine is available only with your doctor's prescription.


Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, mesalamine is used in certain patients with the following medical conditions:


  • Mild or moderate Crohn's disease—for treatment and to prevent it from occurring again.

Before Using Apriso


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies have not been performed on the relationship of age to the effects of mesalamine in the pediatric population. Safety and efficacy have not been established.


Geriatric


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of mesalamine in the elderly. However, elderly patients are more likely to have blood problems (e.g., neutropenia, pancytopenia) and age-related kidney disease, which may require caution and an adjustment in the dose for patients receiving mesalamine.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersBAnimal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Varicella Virus Vaccine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Ardeparin

  • Certoparin

  • Dalteparin

  • Danaparoid

  • Enoxaparin

  • Nadroparin

  • Parnaparin

  • Reviparin

  • Tamarind

  • Tinzaparin

  • Warfarin

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Allergy to aminosalicylates or salicylates (e.g., aspirin)—Should not be used in patients with this condition.

  • Kidney disease, or history of—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

  • Liver disease or

  • Myocarditis (heart disease), history of or

  • Pericarditis (heart disease), history of—Use with caution. May make these conditions worse.

  • Phenylketonuria (PKU)—The Apriso™ capsules contain aspartame, which may require caution in patients with PKU.

  • Pyloric stenosis (tube where food passes out of the stomach is too narrow)—May delay the release of mesalamine into the body.

Proper Use of mesalamine

This section provides information on the proper use of a number of products that contain mesalamine. It may not be specific to Apriso. Please read with care.


Take this medicine exactly as directed by your doctor. Do not take it more often, and do not take it for a longer time than your doctor ordered. Also, do not stop taking this medicine without first checking with your doctor.


Keep taking this medicine for the full time of treatment, even if you begin to feel better after a few days. Do not miss any doses.


You should take the delayed-release tablets with food. All other brands of capsules and tablets can be taken with or without food.


Swallow the capsule or tablet whole. Do not open, break, crush, or chew it before swallowing.


Do not change to another brand without checking with your doctor. The number of capsules or tablets that you take depends on the brand and strength of the medicine. If you refill your medicine and it looks different, check with your pharmacist. One tablet of Asacol® HD 800 milligrams (mg) tablet may not work the same way as two Asacol® 400 mg tablets.


If you are taking the extended-release capsule or the delayed-release tablet, part of the capsule or tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For the treatment of ulcerative colitis:
    • For long-acting oral dosage form (delayed-release tablets):
      • Adults:
        • For Asacol®: 800 milligrams (mg) (two 400 mg tablets) three times a day. For maintenance (long-term) treatment, 1600 mg per day in divided doses.

        • For Asacol® HD: 1600 milligrams (mg) (two 800 mg tablets) three times a day for 6 weeks.

        • For Lialda®: 2.4 to 4.8 grams (two to four tablets) once a day as a single dose with food.


      • Children—Use and dose must be determined by your doctor.


    • For long-acting oral dosage form (extended-release capsules):
      • Adults:
        • For Apriso™: 1.5 grams (four capsules) once a day as a single dose in the morning.

        • For Pentasa®: 1 gram (2 or 4 capsules) four times a day.


      • Children—Use and dose must be determined by your doctor.



  • For prevention of ulcerative colitis:
    • For long-acting oral dosage form (delayed-release tablets):
      • Adults—2.4 grams (two tablets) once a day as a single dose with food.

      • Children—Use and dose must be determined by your doctor.



Missed Dose


If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Store the delayed-release tablets in a tightly-closed container to protect them from moisture. Putting desiccant pouches in the container may also help to keep the tablets from getting moist.


Precautions While Using Apriso


It is important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. Urine or blood tests may be needed to check for unwanted effects.


Check with your doctor right away if you have abdominal or stomach pain, bloody diarrhea, cramps, fever, headache, or a rash while you are using this medicine. These may be symptoms of a condition called mesalamine-induced acute intolerance syndrome.


Do not take antacids (e.g., Amphojel®, Maalox®, Mylanta®, Tums®) while you are taking the Apriso™ extended-release capsules. Using these medicines together may change the amount of medicine that is released in the body.


Tell your doctor if you have had an allergic reaction to sulfasalazine (Azulfidine®).


Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.


Apriso Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


More common
  • Abdominal or stomach pain (severe)

  • bloody diarrhea

  • rectal bleeding

Less common
  • Abdominal or stomach cramps (severe)

  • blurred vision

  • dizziness

  • fever

  • full or bloated feeling

  • headache (severe)

  • nervousness

  • pounding in the ears

  • pressure in the stomach

  • skin rash and itching

  • slow or fast heartbeat

  • swelling of the abdominal or stomach area

  • unusual tiredness or weakness

Rare
  • Anxiety

  • back pain (severe)

  • blue or pale skin

  • chest pain, possibly moving to the left arm, neck, or shoulder

  • chills

  • nausea or vomiting

  • shortness of breath

  • yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:


Symptoms of overdose
  • Confusion

  • deep or fast breathing with dizziness

  • diarrhea (severe or continuing)

  • difficult or labored breathing

  • dizziness or lightheadedness

  • drowsiness (severe)

  • feeling of constant movement of self or surroundings

  • headache (severe or continuing)

  • hearing loss or ringing or buzzing in the ears (continuing)

  • nausea or vomiting (continuing)

  • numbness of the feet, hands, and around the mouth

  • seizures

  • sensation of spinning

  • sweating

  • tightness in the chest

  • wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Abdominal or stomach cramps or pain (mild)

  • diarrhea (mild)

  • headache (mild)

  • runny or stuffy nose

  • sneezing

Less common
  • Acid or sour stomach

  • acne

  • back or joint pain

  • belching

  • difficulty with moving

  • excess air or gas in the stomach or intestines

  • hair loss or thinning of the hair

  • heartburn

  • indigestion

  • loss of appetite

  • muscle pain or stiffness

  • passing gas

  • stomach discomfort or upset

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Apriso side effects (in more detail)



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More Apriso resources


  • Apriso Side Effects (in more detail)
  • Apriso Use in Pregnancy & Breastfeeding
  • Apriso Drug Interactions
  • Apriso Support Group
  • 3 Reviews for Apriso - Add your own review/rating


  • Apriso Extended-Release Capsules MedFacts Consumer Leaflet (Wolters Kluwer)

  • Apriso Consumer Overview

  • Apriso Prescribing Information (FDA)

  • Mesalamine Prescribing Information (FDA)

  • Mesalamine Monograph (AHFS DI)

  • Mesalamine Controlled-Release Capsules MedFacts Consumer Leaflet (Wolters Kluwer)

  • Asacol Prescribing Information (FDA)

  • Asacol Consumer Overview

  • Asacol Delayed-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

  • Asacol HD Prescribing Information (FDA)

  • Asacol HD Delayed-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

  • Canasa Prescribing Information (FDA)

  • Canasa Suppositories MedFacts Consumer Leaflet (Wolters Kluwer)

  • Lialda Prescribing Information (FDA)

  • Lialda Consumer Overview

  • Pentasa Consumer Overview

  • Pentasa Prescribing Information (FDA)

  • Rowasa Prescribing Information (FDA)

  • Rowasa Enema MedFacts Consumer Leaflet (Wolters Kluwer)

  • sfRowasa Prescribing Information (FDA)



Compare Apriso with other medications


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  • Ulcerative Colitis
  • Ulcerative Colitis, Maintenance
  • Ulcerative Proctitis

Tuesday, March 6, 2012

Indocid




Indocid may be available in the countries listed below.


Ingredient matches for Indocid



Cromoglicic Acid

Cromoglicic Acid is reported as an ingredient of Indocid in the following countries:


  • Greece

Indometacin

Indometacin is reported as an ingredient of Indocid in the following countries:


  • Aruba

  • Australia

  • Austria

  • Bahamas

  • Bahrain

  • Barbados

  • Belgium

  • Belize

  • Brazil

  • Cayman Islands

  • Dominican Republic

  • Egypt

  • Ethiopia

  • Finland

  • France

  • Hong Kong

  • Iceland

  • Italy

  • Jamaica

  • Luxembourg

  • Mexico

  • Netherlands

  • Netherlands Antilles

  • Norway

  • Oman

  • Peru

  • Portugal

  • Switzerland

  • Taiwan

  • Trinidad & Tobago

  • Venezuela

Indometacin sodium salt (a derivative of Indometacin) is reported as an ingredient of Indocid in the following countries:


  • Australia

  • Hong Kong

  • Ireland

  • Netherlands

  • New Zealand

  • United Kingdom

International Drug Name Search

Saturday, March 3, 2012

Tigan Intramuscular


Generic Name: trimethobenzamide (Intramuscular route)

trye-meth-oh-BENZ-a-mide

Commonly used brand name(s)

In the U.S.


  • Arrestin

  • Benzacot

  • Stemetic

  • Ticon

  • Tigan

  • Tribenzagan

Available Dosage Forms:


  • Solution

Therapeutic Class: Antiemetic


Pharmacologic Class: Anticholinergic


Uses For Tigan


Trimethobenzamide is used to treat nausea and vomiting .


This medicine is available only with your doctor's prescription .


Before Using Tigan


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


No information is available on the relationship of age to the effects of intramuscular trimethobenzamide in the pediatric population. However, because of this medication's toxicity, use in children is contraindicated. Intramuscular trimethobenzamide should never be used in children .


Geriatric


No information is available on whether the risk of trimethobenzamide-induced adverse effects is increased in the elderly. However, because of this medication's toxicity, it should be used with caution, after less toxic alternatives have been considered and/or found ineffective. Recommended doses should not be exceeded, and the patient should be carefully monitored during therapy .


Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.


  • Metoclopramide

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Dehydration or

  • Electrolyte imbalance (high or low levels of minerals in the blood) or

  • High fever or

  • Intestinal infection, severe—May cause side effects to become worse .

Proper Use of trimethobenzamide

This section provides information on the proper use of a number of products that contain trimethobenzamide. It may not be specific to Tigan. Please read with care.


Trimethobenzamide is only used to relieve or prevent nausea and vomiting. A nurse or other trained health professional will give you this medicine. This medicine is given as a shot into one of your muscles .


Your doctor may only give you a few doses of this medicine until your condition improves, and then may switch you to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor .


Precautions While Using Tigan


Trimethobenzamide will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicines for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicines; prescription pain medicines or narcotics; barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of these medicines while you are using trimethobenzamide .


This medicine may cause some people to become dizzy, lightheaded, drowsy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert .


Tigan Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


Rare
  • Body spasm, with head and heels bent backward and body bowed forward

  • convulsions (seizures)

  • depression

  • shakiness or tremors

  • skin rash

  • sore throat or fever

  • unusual tiredness

  • vomiting (severe or continuing)

  • yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Drowsiness

Less common
  • Blurred vision

  • diarrhea

  • dizziness

  • headache

  • muscle cramps

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Tigan Intramuscular side effects (in more detail)



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More Tigan Intramuscular resources


  • Tigan Intramuscular Side Effects (in more detail)
  • Tigan Intramuscular Use in Pregnancy & Breastfeeding
  • Drug Images
  • Tigan Intramuscular Drug Interactions
  • Tigan Intramuscular Support Group
  • 0 Reviews for Tigan Intramuscular - Add your own review/rating


Compare Tigan Intramuscular with other medications


  • Nausea/Vomiting

Friday, March 2, 2012

Indomethacin Capsules



Pronunciation: IN-doe-METH-a-sin
Generic Name: Indomethacin
Brand Name: Indocin

Indomethacin Capsules is a nonsteroidal anti-inflammatory drug (NSAID). It may cause an increased risk of serious and sometimes fatal heart and blood vessel problems (eg, heart attack, stroke). The risk may be greater if you already have heart problems or if you take Indomethacin Capsules for a long time. Do not use Indomethacin Capsules right before or after bypass heart surgery.


Indomethacin Capsules may cause an increased risk of serious and sometimes fatal stomach ulcers and bleeding. Elderly patients may be at greater risk. This may occur without warning signs.





Indomethacin Capsules is used for:

Treating moderate to severe rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is used to treat gout or certain types of bursitis and tendonitis. It may also be used for other conditions as determined by your doctor.


Indomethacin Capsules is an NSAID. Exactly how it works is not known. It may block certain substances in the body that are linked to inflammation. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes those symptoms.


Do NOT use Indomethacin Capsules if:


  • you are allergic to any ingredient in Indomethacin Capsules

  • you have had a severe allergic reaction (eg, severe rash, hives, trouble breathing, growths in the nose, dizziness) to aspirin or an NSAID (eg, ibuprofen, celecoxib)

  • you have recently had or will be having bypass heart surgery

  • you are taking diflunisal, another NSAID (eg, ibuprofen), or triamterene

  • you are in the last 3 months of pregnancy

Contact your doctor or health care provider right away if any of these apply to you.



Before using Indomethacin Capsules:


Some medical conditions may interact with Indomethacin Capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a history of kidney or liver disease, diabetes, or stomach or bowel problems (eg, bleeding, perforation, ulcers, inflammation)

  • if you have a history of swelling or fluid buildup, depression, mental or mood problems, seizures, Parkinson disease, asthma, growths in the nose (nasal polyps), or mouth inflammation

  • if you have high blood pressure, a blood disorder, bleeding or clotting problems, heart problems (eg, heart failure), or blood vessel disease, or if you are at risk for any of these diseases

  • if you have poor health, dehydration or low fluid volume, low blood sodium levels, or high blood potassium levels, you drink alcohol, or you have a history of alcohol abuse

Some MEDICINES MAY INTERACT with Indomethacin Capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Anticoagulants (eg, warfarin), corticosteroids (eg, prednisone), diflunisal, heparin, other NSAIDs (eg, ibuprofen), salicylates (eg, aspirin), or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because the risk of stomach bleeding may be increased

  • Potassium-sparing diuretics (eg, spironolactone, triamterene) because the risk of kidney problems or increased blood potassium levels may be increased

  • Cyclophosphamide because low blood sodium levels may occur

  • Probenecid because it may increase the risk of Indomethacin Capsules's side effects

  • Cyclosporine, digoxin, lithium, methotrexate, quinolones (eg, ciprofloxacin), or sulfonylureas (eg, glipizide) because the risk of their side effects may be increased by Indomethacin Capsules

  • Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), angiotensin receptor blockers (eg, losartan), beta-blockers (eg, propranolol), or diuretics (eg, furosemide, hydrochlorothiazide) because their effectiveness may be decreased by Indomethacin Capsules

This may not be a complete list of all interactions that may occur. Ask your health care provider if Indomethacin Capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Indomethacin Capsules:


Use Indomethacin Capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Indomethacin Capsules comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Indomethacin Capsules refilled.

  • Take Indomethacin Capsules by mouth with food. This may not lower the risk of stomach or bowel problems (eg, bleeding, ulcers). Talk with your doctor if you have persistent stomach upset.

  • Take Indomethacin Capsules with a full glass of water (8 oz/240 mL) as directed by your doctor.

  • If you miss a dose of Indomethacin Capsules and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Indomethacin Capsules.



Important safety information:


  • Indomethacin Capsules may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Indomethacin Capsules with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Serious stomach ulcers or bleeding can occur with the use of Indomethacin Capsules. Taking it in high doses or for a long time, smoking, or drinking alcohol increases the risk of these side effects. Taking Indomethacin Capsules with food will NOT reduce the risk of these effects. Contact your doctor or emergency room at once if you develop severe stomach or back pain; black, tarry stools; vomit that looks like blood or coffee grounds; or unusual weight gain or swelling.

  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.

  • Indomethacin Capsules is an NSAID. Before you start taking any new medicine, read the ingredients. If it also has an NSAID (eg, ibuprofen) in it, check with your doctor. If you are not sure, check with your doctor or pharmacist.

  • Do not take aspirin while you are using Indomethacin Capsules unless your doctor tells you to.

  • Indomethacin Capsules may interfere with certain lab tests. Be sure your doctor and lab personnel know that you take Indomethacin Capsules.

  • Lab tests, including kidney function, complete blood cell counts, and blood pressure, may be done to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.

  • Use Indomethacin Capsules with caution in the ELDERLY; they may be more sensitive to its effects, including stomach bleeding, kidney problems, confusion, or mental changes.

  • Indomethacin Capsules should be used with extreme caution in CHILDREN younger than 15 year old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: Indomethacin Capsules may harm the fetus. Do not use it during the last 3 months of pregnancy. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Indomethacin Capsules while you are pregnant. Indomethacin Capsules is found in breast milk. Do not breast-feed while you are taking Indomethacin Capsules.


Possible side effects of Indomethacin Capsules:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Constipation; diarrhea; dizziness; drowsiness; gas; headache; heartburn; nausea; stomach upset.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; trouble breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in the urine; bloody or black, tarry stools; change in the amount of urine produced; chest pain; confusion; dark urine; depression; fainting; fast or irregular heartbeat; fever, chills, or persistent sore throat; mental or mood changes; numbness of an arm or leg; one-sided weakness; rectal bleeding; red, swollen, blistered, or peeling skin; ringing in the ears; seizures; severe headache or dizziness; severe or persistent stomach pain or nausea; severe vomiting; shortness of breath; sudden or unexplained weight gain; swelling of hands, legs, or feet; unusual bruising or bleeding; unusual joint or muscle pain; unusual tiredness or weakness; unusual vaginal bleeding; vision or speech changes; vomit that looks like coffee grounds; yellowing of the skin or eyes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Indomethacin side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include confusion; decreased urination; loss of consciousness; seizures; severe dizziness or drowsiness; severe headache; severe nausea or stomach pain; slow or troubled breathing; unusual bleeding or bruising; vomit that looks like coffee grounds.


Proper storage of Indomethacin Capsules:

Store Indomethacin Capsules at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Indomethacin Capsules out of the reach of children and away from pets.


General information:


  • If you have any questions about Indomethacin Capsules, please talk with your doctor, pharmacist, or other health care provider.

  • Indomethacin Capsules is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is summary only. It does not contain all information about Indomethacin Capsules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Indomethacin resources


  • Indomethacin Side Effects (in more detail)
  • Indomethacin Dosage
  • Indomethacin Use in Pregnancy & Breastfeeding
  • Drug Images
  • Indomethacin Drug Interactions
  • Indomethacin Support Group
  • 35 Reviews for Indomethacin - Add your own review/rating


Compare Indomethacin with other medications


  • Ankylosing Spondylitis
  • Back Pain
  • Bartter Syndrome
  • Bursitis
  • Cluster Headaches
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  • Gitelman Syndrome
  • Gout, Acute
  • Langerhans' Cell Histiocytosis
  • Osteoarthritis
  • Pain
  • Patent Ductus Arteriosus
  • Rheumatoid Arthritis
  • Sciatica
  • Tendonitis