Permoxin

Permoxin may be available in the countries listed below.

In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Permoxin

Permethrin

Permethrin is reported as an ingredient of Permoxin in the following countries:

• Australia


• New Zealand

International Drug Name Search

Lozatan

Lozatan may be available in the countries listed below.

Ingredient matches for Lozatan

Losartan

Losartan potassium salt (a derivative of Losartan) is reported as an ingredient of Lozatan in the following countries:

• Greece

International Drug Name Search

Cebroton

Cebroton may be available in the countries listed below.

Ingredient matches for Cebroton

Citicoline

Citicoline sodium salt (a derivative of Citicoline) is reported as an ingredient of Cebroton in the following countries:

• Italy

International Drug Name Search

Iodio + Glicerolo

Iodio + Glicerolo may be available in the countries listed below.

Ingredient matches for Iodio + Glicerolo

Iodine

Iodine is reported as an ingredient of Iodio + Glicerolo in the following countries:

• Italy

Potassium Iodide

Potassium Iodide is reported as an ingredient of Iodio + Glicerolo in the following countries:

• Italy

International Drug Name Search

Prostanorm

Prostanorm may be available in the countries listed below.

Ingredient matches for Prostanorm

Finasteride

Finasteride is reported as an ingredient of Prostanorm in the following countries:

• Serbia

International Drug Name Search

Dasatinib

Pronunciation: da-SA-ti-nib
Generic Name: Dasatinib
Brand Name: Sprycel

Dasatinib is used for:

Treating certain types of leukemia. It may also be used for other conditions as determined by your doctor.

Dasatinib is a tyrosine kinase inhibitor. It works by blocking proteins that cause the rapid growth of certain types of leukemia cells. This helps the bone marrow to start making normal blood cells again.

Do NOT use Dasatinib if:

• you are allergic to any ingredient in Dasatinib


• you are taking an H₂ blocker (eg, famotidine), a proton pump inhibitor (eg, omeprazole), or St. John's wort

Contact your doctor or health care provider right away if any of these apply to you.

Before using Dasatinib:

Some medical conditions may interact with Dasatinib. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, other substances


• if you are lactose intolerant. Dasatinib contains lactose


• if you have liver problems, lung problems (eg, pulmonary arterial hypertension [PAH]), blood problems (eg, anemia, low blood potassium or magnesium levels, low platelet levels, low white blood cell levels), immune system problems, heart problems, or irregular heartbeat (eg, prolonged QT interval, congenital long QT syndrome)


• if you have not previously received treatment with imatinib or other therapies for leukemia

Some MEDICINES MAY INTERACT with Dasatinib. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Anticoagulants (eg, heparin, warfarin), antiplatelet medicines (eg, clopidogrel), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) because the risk of bleeding problems may be increased


• Anthracyclines (eg, doxorubicin), antiarrhythmics (eg, amiodarone, quinidine), arsenic, astemizole, bepridil, chloroquine, citalopram, cisapride, crizotinib, dolasetron, domperidone, doxepin, droperidol, halofantrine, haloperidol, iloperidone, maprotiline, methadone, nortriptyline, ondansetron, paliperidone, pentamidine, phenothiazines (eg, thioridazine), pimozide, quetiapine, quinolone antibiotics (eg, levofloxacin), romidepsin, tacrolimus, terfenadine, toremifene, vandetanib, or ziprasidone because the risk of severe and possibly fatal irregular heartbeat may be increased


• Azole antifungals (eg, ketoconazole), macrolide antibiotics (eg, clarithromycin, erythromycin), nefazodone, protease inhibitors (eg, boceprevir, ritonavir), or telithromycin because they may increase the risk of Dasatinib's side effects


• Carbamazepine, dexamethasone, H₂ blockers (eg, famotidine), hydantoins (eg, phenytoin), nevirapine, phenobarbital, primidone, proton pump inhibitors (eg, omeprazole), rifamycins (eg, rifabutin, rifampin), or St. John's wort because they may decrease Dasatinib's effectiveness


• Alfentanil, cyclosporine, ergot derivatives (eg, ergotamine), fentanyl, or sirolimus because the risk of their side effects may be increased by Dasatinib

This may not be a complete list of all interactions that may occur. Ask your health care provider if Dasatinib may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Dasatinib:

Use Dasatinib as directed by your doctor. Check the label on the medicine for exact dosing instructions. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Dasatinib. Talk to your pharmacist if you have questions about this information.


• Take Dasatinib by mouth with or without food.


• Swallow Dasatinib whole. Do not break, crush, or chew before swallowing.


• Do not eat grapefruit or drink grapefruit juice while you use Dasatinib.


• Do not take an antacid within 2 hours before or 2 hours after you take Dasatinib.


• Take Dasatinib at the same time each day.


• Do not change your dose or stop taking Dasatinib without first talking with your doctor.


• If you miss a dose of Dasatinib, take your next scheduled dose at its regular time. Do not take 2 doses at once. Contact your doctor or pharmacist if you are unsure of what to do.

Ask your health care provider any questions you may have about how to use Dasatinib.

Important safety information:

• Dasatinib may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Dasatinib with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Women who may become pregnant should use effective birth control while taking Dasatinib. Check with your doctor if you have questions about using birth control.


• Women who are pregnant should avoid exposure to Dasatinib if the tablet is accidentally crushed or broken.


• If you experience nausea, vomiting, diarrhea, or loss of appetite, talk with your doctor about ways to lessen these effects.


• Dasatinib may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.


• Dasatinib may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.


• Dasatinib may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Dasatinib. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.


• Dasatinib may increase the risk of developing high blood pressure in your lungs (pulmonary arterial hypertension [PAH]). This may occur at anytime after starting Dasatinib, including after more than 1 year of treatment. Discuss any questions or concerns with your doctor. Contact your doctor right away if you experience shortness of breath or trouble breathing, unusual tiredness, or unusual swelling.


• Tell your doctor or dentist that you take Dasatinib before you receive any medical or dental care, emergency care, or surgery.


• Lab tests, including liver, lung, and heart function; blood electrolytes; and complete blood cell counts, may be performed while you use Dasatinib. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Dasatinib with caution in the ELDERLY; they may be more sensitive to its effects.


• Dasatinib should be used with extreme caution in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Dasatinib may cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if Dasatinib is found in breast milk. Do not breast-feed while taking Dasatinib.

Possible side effects of Dasatinib:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry eyes; fatigue; hair loss; headache; joint or muscle pain; loss of appetite; nausea; stomach pain; taste changes; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry, or bright red stools; blood in the vomit; burning, numbness, or tingling; calf or leg pain, tenderness, or swelling; change in the amount of urine produced; chest, jaw, or left arm pain; confusion; dark urine; dry cough; fainting; irregular heartbeat; irritation or sores in the mouth; mood or mental changes (eg, depression); numbness of an arm or leg; red, swollen, peeling, or blistered skin; ringing in the ears; seizures; severe or persistent diarrhea, headache, muscle or bone pain, nausea, stomach pain, or vomiting; severe or persistent tiredness or weakness; shortness of breath; signs of bleeding in the brain (eg, slurred speech, one-sided weakness, muscle weakness, loss of consciousness); signs of infection (eg, fever, chills, sore throat); unusual bruising or bleeding; unusual swelling or weight gain; vision changes (eg, blurred vision, decreased vision clearness); vomit that looks like coffee grounds; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Dasatinib side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Dasatinib:

Store Dasatinib at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Dasatinib out of the reach of children and away from pets.

General information:

• If you have any questions about Dasatinib, please talk with your doctor, pharmacist, or other health care provider.


• Dasatinib is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Dasatinib. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Dasatinib resources

• Dasatinib Side Effects (in more detail)
• Dasatinib Dosage
• Dasatinib Use in Pregnancy & Breastfeeding
• Dasatinib Drug Interactions
• Dasatinib Support Group
• 6 Reviews for Dasatinib - Add your own review/rating

• Dasatinib Professional Patient Advice (Wolters Kluwer)


• Dasatinib Monograph (AHFS DI)


• dasatinib Advanced Consumer (Micromedex) - Includes Dosage Information


• Sprycel Prescribing Information (FDA)


• Sprycel Consumer Overview

Compare Dasatinib with other medications

• Acute Lymphoblastic Leukemia
• Chronic Myelogenous Leukemia
• Leukemia

Osaston

Osaston may be available in the countries listed below.

Ingredient matches for Osaston

Alendronic Acid

Alendronic Acid sodium trihydrate (a derivative of Alendronic Acid) is reported as an ingredient of Osaston in the following countries:

• Greece

International Drug Name Search

Cetrivax

Cetrivax may be available in the countries listed below.

Ingredient matches for Cetrivax

Cetirizine

Cetirizine dihydrochloride (a derivative of Cetirizine) is reported as an ingredient of Cetrivax in the following countries:

• Poland

International Drug Name Search

Trant

Trant may be available in the countries listed below.

Ingredient matches for Trant

Trazodone

Trazodone hydrochloride (a derivative of Trazodone) is reported as an ingredient of Trant in the following countries:

• Chile

International Drug Name Search