Pronunciation: floo-KON-a-zole
Generic Name: Fluconazole
Brand Name: Diflucan
Diflucan Single-Dose Tablets are used for:
Treating vaginal yeast infections. It may also be used for other conditions as determined by your doctor.
Diflucan Single-Dose Tablets are an azole antifungal. It kills sensitive fungi by interfering with the formation of the fungal cell membrane and weakening it.
Do NOT use Diflucan Single-Dose Tablets if:
- you are allergic to any ingredient in Diflucan Single-Dose Tablets
- you are taking astemizole, cisapride, clopidogrel, an ergot alkaloid (eg, ergotamine), erythromycin, pimozide, quinidine, terfenadine, or voriconazole
Contact your doctor or health care provider right away if any of these apply to you.
Before using Diflucan Single-Dose Tablets:
Some medical conditions may interact with Diflucan Single-Dose Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines or other substances
- if you have had an allergic reaction to another azole antifungal (eg, itraconazole)
- if you have a history of liver or kidney problems, or heart problems (eg, irregular heartbeat, structural heart problems)
- if you have a weakened immune system, HIV infection, diabetes, cancer, or blood electrolyte problems (eg, low blood potassium or magnesium levels)
Some MEDICINES MAY INTERACT with Diflucan Single-Dose Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Antiarrhythmics (eg, amiodarone, quinidine, sotalol), arsenic, astemizole, cisapride, domperidone, macrolide antibiotics (eg, erythromycin), pimozide, quinolones (eg, levofloxacin), serotonin (5-HT1) receptor agonists (eg, eletriptan), terfenadine, or vandetanib because the risk of severe irregular heartbeat (eg, QT prolongation) may be increased
- Rifabutin because the risk of certain eye problems (eg, uveitis) may be increased
- Macrolide immunosuppressants (eg, sirolimus, tacrolimus) because the risk of kidney problems may be increased
- Proton pump inhibitors (eg, omeprazole) or rifamycins (eg, rifampin) because they may decrease Diflucan Single-Dose Tablets's effectiveness
- Clopidogrel, hormonal birth control (eg, birth control pills), or losartan because their effectiveness may be decreased by Diflucan Single-Dose Tablets
- Amphotericin B, anticoagulants (eg, warfarin), benzodiazepines (eg, alprazolam, midazolam), buspirone, certain calcium channel blockers (eg, amlodipine, felodipine, nifedipine), carbamazepine, colchicine, cyclophosphamide, cyclosporine, eplerenone, ergot alkaloids (eg, ergotamine), everolimus, fentanyl, halofantrine, haloperidol, certain HMG-CoA reductase inhibitors or "statins" (eg, atorvastatin, fluvastatin, simvastatin), hydantoins (eg, phenytoin), lurasidone, methadone, muscarinic antagonists (eg, solifenacin, tolterodine), nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, celecoxib, ibuprofen), prednisone, ramelteon, ranolazine, sulfonylureas (eg, glipizide, glyburide, tolbutamide), theophylline, tolvaptan, tretinoin, tricyclic antidepressants (eg, amitriptyline), vinca alkaloids (eg, vinblastine, vincristine), voriconazole, or zidovudine because the risk of their side effects may be increased by Diflucan Single-Dose Tablets
This may not be a complete list of all interactions that may occur. Ask your health care provider if Diflucan Single-Dose Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Diflucan Single-Dose Tablets:
Use Diflucan Single-Dose Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Diflucan Single-Dose Tablets by mouth with or without food.
- Take Diflucan Single-Dose Tablets at least 2 hours before proton pump inhibitors (eg, omeprazole).
- To clear up your infection completely, take Diflucan Single-Dose Tablets for the full course of treatment. Keep taking it even if you feel better in a few days.
- For some women, it may take longer than 24 hours for symptom relief to begin. If your symptoms have not gotten better within 3 to 5 days, you should call your doctor.
- Only 1 dose of Diflucan Single-Dose Tablets are usually required. If your doctor has prescribed more than 1 dose of Diflucan Single-Dose Tablets and you miss your dose, take it as soon as possible. Continue to use Diflucan Single-Dose Tablets as directed by your doctor. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Diflucan Single-Dose Tablets.
Important safety information:
- Diflucan Single-Dose Tablets may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Diflucan Single-Dose Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Diflucan Single-Dose Tablets has been known to cause rare cases of serious liver damage, including death, mainly in patients with serious medical conditions. Liver damage caused by Diflucan Single-Dose Tablets has not been attributed to total daily dose, length of therapy, or sex or age of patient. This type of liver damage may or may not be reversible when Diflucan Single-Dose Tablets are stopped. Contact your doctor right away if you experience dark urine, loss of appetite, pale stools, severe stomach pain, or yellowing of the skin or eyes.
- Diflucan Single-Dose Tablets only works against fungi; it does not treat viral infections (eg, the common cold) or bacterial infections.
- Tell your doctor or dentist that you take Diflucan Single-Dose Tablets before you receive any medical or dental care, emergency care, or surgery.
- Be sure to use Diflucan Single-Dose Tablets for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The fungus could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
- Hormonal birth control (eg, birth control pills) may not work as well while you are using Diflucan Single-Dose Tablets. To prevent pregnancy, use an extra form of birth control (eg, condoms).
- Lab tests, including liver and kidney function, may be performed while you use Diflucan Single-Dose Tablets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use Diflucan Single-Dose Tablets with caution in the ELDERLY; they may be more sensitive to its effects.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Diflucan Single-Dose Tablets while you are pregnant. Diflucan Single-Dose Tablets are found in breast milk. If you are or will be breast-feeding while you use Diflucan Single-Dose Tablets, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Diflucan Single-Dose Tablets:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Changes in taste; diarrhea; dizziness; headache; indigestion; mild stomach pain; nausea; vomiting.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness; wheezing); burning, numbness, or tingling; dark urine; fever, chills, or persistent sore throat; irregular heartbeat; loss of appetite; muscle pain, weakness, or cramping; pale stools; red, swollen, blistered, or peeling skin; seizures; severe or persistent diarrhea, nausea, or vomiting; swelling of the hands; unusual bruising or bleeding; unusual or severe stomach pain; unusual tiredness; yellowing of the eyes or skin.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
See also: Diflucan side effects (in more detail)
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include changes in behavior; hallucinations.
Proper storage of Diflucan Single-Dose Tablets:
Store Diflucan Single-Dose Tablets below 86 degrees F (30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Diflucan Single-Dose Tablets out of the reach of children and away from pets.
General information:
- If you have any questions about Diflucan Single-Dose Tablets, please talk with your doctor, pharmacist, or other health care provider.
- Diflucan Single-Dose Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information is a summary only. It does not contain all information about Diflucan Single-Dose Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
More Diflucan resources
- Diflucan Side Effects (in more detail)
- Diflucan Use in Pregnancy & Breastfeeding
- Drug Images
- Diflucan Drug Interactions
- Diflucan Support Group
- 26 Reviews for Diflucan - Add your own review/rating
Compare Diflucan with other medications
- Blastomycosis
- Bone Marrow Transplantation
- Candida Infections, Systemic
- Candida Urinary Tract Infection
- Chronic Mucocutaneous Candidiasis
- Coccidioidomycosis
- Coccidioidomycosis, Meningitis
- Cryptococcal Meningitis, Immunocompetent Host
- Cryptococcal Meningitis, Immunosuppressed Host
- Cryptococcosis
- Esophageal Candidiasis
- Fungal Infection Prophylaxis
- Fungal Infection, Internal and Disseminated
- Fungal Peritonitis
- Fungal Pneumonia
- Histoplasmosis
- Onychomycosis, Fingernail
- Onychomycosis, Toenail
- Oral Thrush
- Tinea Versicolor
- Vaginal Yeast Infection
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